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Tech Note from SP Scientific: Drug Discovery Workflow for PROTAC with a Focus on Eliminating Bottlenecks in Evaporation
by biopharmaelena in Application Notes
An emerging modality of therapeutics called PROteolysis TArgeting Chimeras (PROTACs) could enable the design of new drugs targeting “undruggable” proteins, this development has led to great interest in the pharmaceutical and biotechnology industries. However, synthesis of PROTACs requires numerous evaporation steps, causing bottlenecks in their production and slowing the drug development process.
This article introduces PROTACs and the benefits they can offer to the drug discovery field, before discussing how the issues with their synthesis can be overcome.
Below you will find a copy of the whitepaper and if you would like to discover more, please get in touch.
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