Viewing posts categorised under: Application and Tech Notes
Webinar Technote: PROTAC Technology for Novel Drug Discovery
Take a look at this Webinar Technote from Biopharma Group & SP Scientific which details the use of PROTAC Technology for Novel Drug Discovery.
To read the complete Technote, click the image bel...Read more
This article was written by Richard Lewis for BPS Crowthorne and was featured on P.32 in Issue 2 of Manufacturing & Supply Chain Magazine
Data Rich Processing - The Growing Necessity of R&D to GMP Manufacture
Improved diagnosis is driving pre...Read more
White Paper from SP Scientific: Putting Fill-Finish Customization Into Your Line of Sight
Take a look at this new white paper from John Erdner at SP Scientific which tackles the challenges of small-batch manufacturing in fill-finish programs.
To read the complete white paper, click the image ...Read more
An emerging modality of therapeutics called PROteolysis TArgeting Chimeras (PROTACs) could enable the design of new drugs targeting “undruggable” proteins, this development has led to great interest in the pharmaceutical and biotechnology industries. However, synthesis of PROTACs requires numerou...Read more
White Paper from SP Scientific: Adoption of Controlled Ice Nucelation Technology, ControLyo
Take a look at this new white paper from Ian Whitehall at SP Scientific which discussed how employing controlled nucleation technology (ControLyo) can offer the benefi...Read more
Could the search for novel antibiotics from marine organisms be the next best approach?
Contrary to popular belief, the past two decades have seen an increase in the use of marine natural products in the field of drug discovery. In this study, drug like molecule mixtures were fractioned using Se...Read more
Have you considered the Prep SFC100 for your chromatography needs yet?
Demonstrating three studies in which Sepiatec's compact Prep SFC100 system can be used, this application note exploits the versatility of the system. It's capability to handle a range of preparative separations combined with ...Read more
A Study on the Selection of Modifiers and their impact on Enantioselectivity in Chiral Stationary Phases (CSPs)
When trying to find an analytical SFC method that can resolve two specific isomers, this process often involves screening different column and mobile phase combinations. To increase ef...Read more
Extracts of the Chinese Herbal Remedy Gymnema sylvestre Inhibit the Sodium‐Dependent Glucose Transporter 1
By Yu Wang, Corinna Dawid, Gabor Kottra, Stephen Pickrahn, Hannelore Daniel and Thomas Hofmann, Technische Universität München; Alison Wake, Genevac Ltd.
Hyperglycemia ...Read more
Avestin Emulsiflex: Supporting the frontiers of Cancer research
Use of Avestin Liposome Extrusion.
Bacteria can cause many different types of infections as they have many virulence factors for example adherence proteins, capsules, biofilm formation, endotoxi...Read more