Viewing posts categorised under: Application Notes

Webinar Technote from Biopharma Group & SP Scientific: PROTAC Technology for Novel Drug Discovery

by biopharmaelena in Application Notes

[vc_row][vc_column][vc_column_text] Webinar Technote: PROTAC Technology for Novel Drug Discovery Take a look at this Webinar Technote from Biopharma Group & SP Scientific which details the use of PROTAC Technology for Novel Drug Discovery. To read the complete Technote, click the image bel...Read more

Data Rich Processing – The Growing Necessity of R&D to GMP Manufacture

by biopharmaelena in App notes & Scientific posters, Application Notes

[vc_row][vc_column][vc_column_text] This article was written by Richard Lewis for BPS Crowthorne and was featured on P.32 in Issue 2 of Manufacturing & Supply Chain Magazine   Data Rich Processing - The Growing Necessity of R&D to GMP Manufacture Improved diagnosis is driving pre...Read more

Putting Fill-Finish Customization Into Your Line of Sight

by biopharmaszymon in Application Notes

White Paper from SP Scientific: Putting Fill-Finish Customization Into Your Line of Sight Take a look at this new white paper from John Erdner at SP Scientific which tackles the challenges of small-batch manufacturing in fill-finish programs. To read the complete white paper, click the image ...Read more

Tech Note from SP Scientific: Drug Discovery Workflow for PROTAC with a Focus on Eliminating Bottlenecks in Evaporation

by biopharmaelena in Application Notes

An emerging modality of therapeutics called PROteolysis TArgeting Chimeras (PROTACs) could enable the design of new drugs targeting “undruggable” proteins, this development has led to great interest in the pharmaceutical and biotechnology industries. However, synthesis of PROTACs requires numerou...Read more

How Controlled Ice Nucleation Can Improve Product Quality & Reduce Cycle Run Time

by biopharmacharis in Application Notes, Uncategorized

[vc_row][vc_column][vc_column_text] White Paper from SP Scientific: Adoption of Controlled Ice Nucelation Technology, ControLyo Take a look at this new white paper from Ian Whitehall at SP Scientific which discussed how employing controlled nucleation technology (ControLyo) can offer the benefi...Read more

Optimised Marine Natural Products Discovery and Screening: Search for Novel “Superbug” Antiobiotics

by in Application Notes

Could the search for novel antibiotics from marine organisms be the next best approach? Contrary to popular belief, the past two decades have seen an increase in the use of marine natural products in the field of drug discovery. In this study, drug like molecule mixtures were fractioned using Se...Read more

New Preparative SFC System for Applications in Chiral Compound Purification

by in Application Notes

Have you considered the Prep SFC100 for your chromatography needs yet? Demonstrating three studies in which Sepiatec's compact Prep SFC100 system can be used, this application note exploits the versatility of the system. It's capability to handle a range of preparative separations combined with ...Read more

Impact on Modifier Selection on Enantioselectivity in SFC

by in Application Notes

A Study on the Selection of Modifiers and their impact on Enantioselectivity in Chiral Stationary Phases (CSPs) When trying to find an analytical SFC method that can resolve two specific isomers, this process often involves screening different column and mobile phase combinations. To increase ef...Read more

Application Note from Genevac – Extracts of Gymnema sylvestre Inhibit the Sodium‐Dependent Glucose Transporter 1

by biopharmacharis in Application Notes

Extracts of the Chinese Herbal Remedy Gymnema sylvestre Inhibit the Sodium‐Dependent Glucose Transporter 1 By Yu Wang, Corinna Dawid, Gabor Kottra, Stephen Pickrahn, Hannelore Daniel and Thomas Hofmann, Technische Universität München; Alison Wake, Genevac Ltd. Introduction Hyperglycemia ...Read more

Avestin Emulsiflex: Supporting the frontiers of Cancer research

by in Application Notes, Biopharma Process Systems

  Case Study Avestin Emulsiflex: Supporting the frontiers of Cancer research Use of Avestin Liposome Extrusion.   Background Bacteria can cause many different types of infections as they have many virulence factors for example adherence proteins, capsules, biofilm formation, endotoxi...Read more