Showing posts tagged with: fractionation

Optimal Drying of HPLC fractions

by in Application Notes, BPS News

Part 3 Controlling the pressure Another crucial parameter to consider when drying water /ACN HPLC fractions using a centrifugal evaporator is pressure control. [caption id="attachment_3514" align="alignleft" width="300"] Figure 3: Boiling point of water/ACN mixes at different pressures[/caption...Read more

Optimal Drying of HPLC fractions

by in BPS News, BPS Right Sidebar Content

July 2014 In pharmaceutical and chemical synthesis laboratories, high performance liquid chromatography (HPLC) is probably the most frequently used analytical separation technique. A widespread and growing application for HPLC is for product purification following chemical synthesis. Common HPL...Read more

Optimal Drying of HPLC Fractions

by in Application Notes, BPS News

Part 2 Even though mixtures of water/ACN alone may not bump, the addition of actual compounds sometimes changes this. Bumping is preventable by employing a controlled vacuum ramp to the centrifugal evaporator when initially pumping down, and increasing the centrifugal force to greater than 450G....Read more

HPLC Sample Preparation for Best Results

by in BPS News, BPS News Cat 1

High performance liquid chromatography (HPLC) is one of the most frequently used analytical separation techniques. A widespread and growing application for HPLC is for product purification following chemical synthesis. Centrifugal evaporation is an ideal technique for drying HPLC fractions as (wi...Read more