Five questions to ask when sourcing an R&D freeze dryer

by in Uncategorized

May 2015 Freeze dryers can be complicated pieces of specialised equipment, with controlled heating, cooling and vacuum interacting with each other to provide the best drying conditions. They are used for many different types of product and there are therefore a variety of different types of syst...Read more

‘Introduction to Homogenisation’ Guide Now Available

by in BPS News, BPS Right Sidebar Content

High pressure homogenisation is a key technology  for particle size reduction, particle or suspension stability, sample homogeneity and nanomolecular disruption. The benefits of this technology include extraction of valuable intracellular products and improving shelf life and potency of pharmaceu...Read more

Diagnostic Reagents: A Different Set of Challenges?

by biopharma-admin in BTL News Cat 1, BTL Right Sidebar Content

May 2015 Biopharma Technology's Dr Kevin Ward will be presenting a webinar in collaboration with SP Scientific's LyoLearn program. This presentation will cover some of the challenges that accompany the formulation and freeze-drying of antibody-based diagnostics and PCR-based diagnostics, toget...Read more

SampleGenie Technology for Large Sample Volumes

by in BPS News, BPS Right Sidebar Content

April 2015 Many applications require the concentration or drying of relatively large samples, for example chromatographic fractions. Traditional processes require the fractions to be concentrated down, re-suspended and re-dried into the relevant vial type before use or storage.This can be a long...Read more

QbD: Building Robust Processes

by biopharma-admin in BTL News, BTL Right Sidebar Content

April 2015 Quality by design (QbD) for lyophilization is about building a robust process that proactively flags critical points and ensures consistent delivery of the best quality product, by minimizing risk and maximizing understanding of the process itself. Regulatory bodies such as the FD...Read more

A Sustainable Freeze Drying Route to Porous Polysaccharides

by in BPS News, BPS Right Sidebar Content

April 2015 Bio-derived polysaccharide aerogels are highly porous materials fabricated from aqueous gels of a range of natural polysaccharides, such as starch, alginic acid, pectin. These materials have attracted increasing attention due to superior physical properties, which make them potential...Read more

Introducing our new North America Senior Sales Manager

by biopharma-admin in BTL News, BTL Right Sidebar Content

March 2015 We are pleased to introduce Mark Lemons as Biopharma Technology’s new Senior Sales Manager for North America. Mark is a graduate of North Carolina State University with a degree in Biochemistry. Along with his strong academic background Mark has worked for a number of analytical ...Read more

Vapour Pressure of Ice

by in Application Notes

The driving force behind freeze drying is the pressure differential between the product chamber and the condenser: the greater the difference, the faster the flow of vapour away from the drying product. The condenser must be significantly colder than the product for effective freeze drying. The t...Read more

Sample Holders: The Right Tool for the Job

by in Application Notes, BPS News

Solvent evaporation is used for an incredibly wide range of applications with many different solutes, solvents and containers. Using the right sample holder for your container type is important to ensure operating efficiency and to prevent product waste. Thermal conductivity [caption id="attachme...Read more

Application Note: High Pressure Homogenisation and Protein Expression

by in Application Notes

Inspiralis is a company based in Norwich which specialises in providing topoisomerases, ligases and other DNA-modifying proteins which are used in the drug-discovery process by the pharmaceutical industry and academia. Topoisomerases are proteins which alter the topology of DNA, preventing it bec...Read more