These laminar airflow tunnels are designed to continuously and efficiently sterilise and depyrogenate pharmaceutical glass containers, in a Class 100 environment at 320ºC.

At this temperature, it takes only 9.5 seconds to reduce the bacterial endotoxin level by 1-log. A 4-log reduction will take 38 seconds, whilst a 6-log reduction will take 57 seconds.

Heat is generated by silicon controlled rectifier elements. Depending on the formal, vials stay inside the sterilising chamber for approximately 6-10 minutes. The recirculated hot air is blown at a speed of approximately 0.7m/s over the vials, and remains within 2°C of its setpoint.

PennTech sterilising tunnels are fully compatible with PennTech vial handling solutions and trayloaders and can be integrated into other existing or new installations.

  • Dimensions
    Varies depending on the model
  • Purpose
    Fully automatic sterilization/depyrogenation tunnels for vials, syringes and ampules
  • Vial Range
    2-100ml
  • Output
    Varies depending on the model
  • Changeover
    Varies depending on the model

Features
– In fewer than 30 minutes, an untreated vial goes from vial washer to sterilizing tunnel to cleanroom, entering in a sterilized microorganism- and pyrogen-free state
– Requires no operator intervention or recontamination
– Typical operating temperature of the tunnel is 320°C
– At this temperature:
– It takes 9.5 seconds to reduce the bacterial endotoxin level by 1-log
– A 4-log reduction will take 38 seconds
– A 6-log reduction in bacterial endotoxin 57 seconds
– Heat is generated by silicon controlled rectifier (SCR) heating elements
– Depending on the format, vials stay inside the sterilizing/depyrogenation chamber for approximately 6-10 minutes
– The recirculated hot air is blown at a speed of approximately 0.7 m/s over the vials and remains within 2°C of its setpoint
– Keeping control over the vials at all times, vials are fed from the vial washer via a sanitary conveyor before gently being pushed into the tunnel by an oscillating pusher
– No format parts are required
– This is essentially a set-it-and-forget-it automatic process
– There are 3 chambers: pre-heating chamber, sterilizing chamber, cooling chamber
– Chambers of the tunnel are separated by gates and the height is automatically set by the PLC as part of the vial recipe
– HEPA filters are tested for efficiency by the “DOP” test procedure (each chamber of the tunnel has provisions to conduct the DOP)
– Each chamber is equipped with a pipe below the filters to allow for particle counting

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