Avestin Inc. boast industry leading homogenisation and extrusion technologies, associated with superior results and a robust, user-friendly manner of operation.

These versatile systems are applied across numerous industries, for applications including:

  • Cell Disruption/Lysis
  • Liposomes
  • Nanoemulsions
  • Particle Size Reduction
  • Nanoparticles

With its unique, dynamic homogenising valve design, from the benchtop (1-5L/hr) to production (500/1000L/hr) scale, comes a smooth homogenisation process with reliability.

Standard operation between 500 – 30,000 psi homogenising pressure; manual or automated.

GMP suitable, the range has 21 CFR Part 11 compliant systems available if required, and an array of documentation/certification options including FAT, SAT, IQ/OQ, surface roughness testing, material traceability and more.

Its success in industry is reflected by the excess of 2000 installations worldwide.

High Pressure Homogeniser Systems

With world-leading scalability, and a versatility in suitable processing volumes, Avestin can be your perfect homogenisation partner, from R&D/benchtop through to scale up operations up to 1000L/hr:

Below are some of the systems available, though please feel free to contact bps@biopharma.co.uk to hear more, and to find out which would be the best system for you.

C3

3L/hr Flow Rate   

10mL min. sample vol

C5

1-5L/hr Flow Rate

10mL min. sample vol

D20

20L/hr Flow Rate 

25mL min. sample vol

C50

15-50L/hr Flow Rate

50mL min. sample vol

C55

55L/hr Flow Rate

100mL min. sample vol

C160

160L/hr Flow Rate

250mL min. sample vol

Biopharma is pleased to exclusively supply products from Avestin Inc. throughout the UK & Ireland.

Latest Additions to the Avestin Inc. Range

The new Automatic Homogenising Pressure Control accessory allows the user to input the desired homogenising pressure onto a touchscreen HMI.

The homogeniser would then ramp up to and maintain that pressure, autonomously.

Advantages include:

  • Improved accuracy in pressure identification via digital display and line graph
  • Mirrors GMP-type processing
  • Reduced homogenising pressure variability
  • More alignment with larger scale processing, to assist with scale-up/scale-down
  • Retrofittable onto existing benchtop units.

Integrated into the machine cabinets of new D20 and larger systems. For existing units and new C3 and C5 units, it exists as a standalone unit.

The Filter/Extruder Accessory for Avestin Homogenisers offers a scale up to the Avestin LiposoFast Series (see below) of liposome extruders.

  • Diameters available:  47 mm, 90 mm, 142 mm
  • Pressure:  up to 8,000 psi (550 bar), depending on specifications

The combination of homogenisation and extrusion often reduces the required number of passes to achieve the desired particle size and size distribution.

For more information, ordering of spare parts or to request a quote:

Liposome Extrusion Systems

LiposoFast-Basic & Stabilizer

Extrusion of unilamellar, homogeneous liposomes in minutes, as a simple, one-step procedure.

Lipid suspensions are forced through a membrane with a fixed pore size.

Capacity:  0.1 mL to 1.0 mL

Over 7,000 instruments sold worldwide.

The optional stabilizer facilitates the repetitive use of the Liposofast-Basic as well as the extrusion of highly concentrated samples.

LiposoFast LF-50

Automated extruder system.

Capacity:  5 mL to 50 mL

Temperature-controlled, jacketed sample cylinder.

The LiposoFast Basic and LiposoFast LF-50 are Available for a FREE TRIAL:  Contact Biopharma and we can have it delivered directly to your door.

Downloadable Homogenisation Booklets

Please click on one of the pictures to below to download your free guide