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Lyotherm3 - Frozen state impedometer

Lyotherm3 - key benefits:

Lyotherm3 combines electrical and thermal techniques, enabling you to do two analyses at the same time:

   -Impedance Analysis (ZSinφ): is a fixed frequency dielectric analysis providing an indication of molecular mobility, including events not picked up by thermal methods like DTA or DSC

   -Differential Thermal Analysis (DTA): measures the difference in temperature between a sample and a reference, highlighting exothermic and endothermic events e.g. crystallisation, eutectic melting and glass transitions

Most accurate analysis data available on the market: the Lyotherm3 simplified operation to increase reliability of results providing you with clear graph data and flexibility during post-analysis

Optimised for frozen state analysis: identifies viscosity changes and critical parameters of samples such as Tg’, crystal transitions, Teu, softening within the frozen structures

Great control and optimization: alarms and liquid nitrogen precision allow greater control over analysis while the updated control unit and wiring design reducing benchtop footprint



Determining critical temperatures is fundamental to our intelligent freeze drying philosophy. Find out how Lyostat and Lyotherm can inform your cycle development process

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Our experienced scientists provide contract research and development services that ensure the success of your project.…

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Learn from Biopharma Technology’s expert tutors at one of many courses held every year worldwide. Visit the Training section for our latest dates.…

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We have taken experience of sales, service and science to provide a handy guide of what to look out for and how to avoid common mistakes.

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Decades of practical process experience

We are outsourcing our product for testing often[…] and getting the satisfactory results from [Biopharma] the company; also availing the additional benefits. We [are] assured to continue the same rapport with your esteemed organization. Thank you for your timely support.

It’s our pleasure to outsource the products for testing with [your] esteemed and well established organization.

Hemant Patil

Research Scientist - Sai Life Sciences Ltd, India

“…fast response to customer requests and provision of a quote. Even though we had delays in confirming the order and providing the samples to btl, the analysis was conducted immediately and results provided swiftly, which is very helpful for a CMO like Vibalogics to keep our customers satisfied.”

Y. Braun

Project Manager - Vibalogics (Germany)

“I worked with BTL and they provided an excellent service to Waters at the development phase of our project.

Both Dr. Laura Ciccolini and Mr. Nick White were very helpful and professional, [they] not only assisted me with the project but also gave me an understanding of the Freeze Drying process. The personnel at BTL are the experts in their field of freeze drying and really supportive to me as a client in our development phase and were really focused in adding value and optimising the process throughout.

I would highly recommend BTL for all Freeze Drying project and would 100% use them again.”

J. O'Neill MPM, PMP

Project Manager HSDx - Waters Technologies, Ireland.

“I would like to give my appreciation for the great service that we received from you [BTL] last year.

When I first contacted your company, my intent was to register myself to one of your Lyo course, unfortunately the regular course schedule didn’t meet my needs so Dr. Laura suggested to try and arrange this course here in Israel. After few email to my colleagues, I was [surprised] to see the actual demand that I got for this course, at the end, I found myself arranging Lyo Bespoke Course for more than 30 colleagues across 3 sites.

Due to Dr. Laura help and dedication, we were able to arrange this course in 3 months […]. The course was great and it met our needs.”

M. Alon

Senior Project Engineer - Omrix Biopharmaceuticals Ltd. Israel

“[Research Scientist] Mervyn did a great job, and we learned useful things about some of our samples during the install and training. We’re excited to have this new tool at our disposal.”

Chief Operating Officer

Reagents Manufacturer

“This is the first time we have used Biopharma and the support, responses and help was excellent.”

Head of Research & Development

Consumer Healthcare Developer