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Vial Washers for the Compounding Pharmacy: Ensuring Preparation Safety

by biopharma-admin in Uncategorized

July 2014 The cleanliness of vials used to contain customized medications is of utmost concern to compounders. Many of today's compounding pharmacists use manual washing or a mechanical dishwasher to clean vials - even those that will be used to contain sterile injectables - but those methods a...Read more

Optimal Drying of HPLC fractions

by biopharma-admin in Uncategorized

Part 3 Controlling the pressure Another crucial parameter to consider when drying water /ACN HPLC fractions using a centrifugal evaporator is pressure control. [caption id="attachment_3514" align="alignleft" width="300"] Figure 3: Boiling point of water/ACN mixes at different pressures[/caption...Read more

Optimal Drying of HPLC fractions

by biopharma-admin in Uncategorized

July 2014 In pharmaceutical and chemical synthesis laboratories, high performance liquid chromatography (HPLC) is probably the most frequently used analytical separation technique. A widespread and growing application for HPLC is for product purification following chemical synthesis. Common HPL...Read more

Optimal Drying of HPLC Fractions

by biopharma-admin in Uncategorized

Part 2 Even though mixtures of water/ACN alone may not bump, the addition of actual compounds sometimes changes this. Bumping is preventable by employing a controlled vacuum ramp to the centrifugal evaporator when initially pumping down, and increasing the centrifugal force to greater than 450G....Read more

Case Study: Friends2Dinner and Powder Filling

by biopharma-admin in Uncategorized

June 2014 "Friends 2 Dinner Ltd was established in Ireland in 2012. Our first product was a Gourmet Mulled Wine infusion consisting of a granulating sugar and spice mix which was initially weighed and packaged by hand. After this product was ordered by a nationwide supermarket chain we required...Read more

Drug Discovery – New challenges, new solutions

by biopharma-admin in Uncategorized

June 2014 Recombinant and heterologous expression of proteins has been a common practice in industry and academia for the last few decades. It is commonly used with technologies including molecular biology, DNA cloning, protein analytics and purification for discovery of new drugs and drug targe...Read more

Stabilisation of Antibody-Drug Conjugates

by biopharma-admin in BTL News, BTL Right Sidebar Content

June 2014 Antibody-Drug Conjugates (ADCs) are a class of therapeutic compounds designed to target cancer cells. They combine the cancer-killing (oncolytic) properties of potent cytotoxic drugs with the targeting capabilities of monoclonal antibodies, meaning that the drug can be delivered to di...Read more

New Life for Old Agrochemicals

by biopharma-admin in BTL News, BTL Right Sidebar Content

June 2014 BTL has recently completed a two-year research project conducted in collaboration with Agform, a developer of novel pest-control agrochemicals, and funded by the Technology Strategy Board (TSB). The problem Farmers are under increasing pressure to provide greater yields with decreasing...Read more

Kinematics & Controls Corporation Achieves ISO9001/AS9100 Certification

by biopharma-admin in Uncategorized

May 2014 Kinematics & Controls Corporation announced today that it has achieved ISO9001/AS9100 certification for its quality management system. After nearly six-months of solid preparation, the final, outside agency audit of the company’s quality management system was conducted at the manufa...Read more

Webinar: Accelerating Product & Process Development with BTL

by biopharma-admin in BTL News, BTL Right Sidebar Content

May 2014 Freeze drying is a science, not an art! Using a range of product characterisation techniques, PAT tools, and experience with hundreds of different types of product, BTL can ensure your project stays on track. Join us for a free webinar exploring how BTL can help streamline your produc...Read more