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Showing posts tagged with: Lyostat

How to prevent your cake from collapsing in Freeze Dried Products?

by biopharmaszymon in BTL News, BTL Right Sidebar Content, Uncategorized

Many drugs are unstable in solution and degrade rapidly over time, therefore they must be freeze dried to produce a suitable stable product which can be shipped and has an acceptable shelf-life for storage. The freeze dried product can be reconstituted to produce a solution containing the drug re...Read more

How To Ensure Your API Is Compatible With Its Formulation

by biopharmacharis in BTL News, BTL Right Sidebar Content, Intelligent Freeze Drying

Years of hard work and research go into developing new APIs, so when it comes to developing one into a new formulation for mass production, careful attention must be paid to its physical and chemical properties. Thorough consideration must go into the excipients to be used, as these can affect ho...Read more

Why pre-formulation studies are crucial to successful drug development

by biopharmacharis in BTL News, BTL News Cat 1, BTL Right Sidebar Content, Intelligent Freeze Drying

As featured in 'International Labmate' - April 2018 - Page 59 Why pre-formulation studies are crucial to successful drug development Understanding the behaviour of a new active pharmaceutical ingredient (API) under various stress conditions is critical to provide a solid foundation for deve...Read more

Lyostat 4 Freeze Drying Microscope Presentation

by biopharma-admin in BTL News, BTL Right Sidebar Content, Presentations

Lyostat4 is the latest freeze drying microscope from BTL. Illumination with virtually maintenance-free LED light provides clearer images for easy analysis. Freeze drying microscopy is used to analyse formulations for freeze drying, enabling cycles to be developed and formulations to be optimised....Read more

Tint Plate Upgrade Provides Clearer Analysis Images

by biopharma-admin in BTL News Cat 1, BTL Right Sidebar Content

April 2014 A first order red filter upgrade is available for the BTL Lyostat3 and Lyostat4LED systems. Lyostat Freeze Drying Microscopy Analysis using Lyostat freeze drying microscopy (FDM) enables a range of important freeze drying characteristics to be identified, including collapse temperatur...Read more

Freeze Drying Simplified: Video

by biopharma-admin in BTL News, BTL Right Sidebar Content

July 2014 Linkam Scientific have created a short video to explain freeze drying and how freeze drying microscopy (Lyostat analysis) can help. Watch the video (opens a new window)>> More about Lyostat>>Read more

Presentation: Instruments for Determination of Critical Temperatures

by biopharma-admin in BTL News, BTL Right Sidebar Content, Presentations

May 2014 The BTL Lyostat and Lyotherm instruments are designed to provide scientists with key data on their products' critical temperatures. This information is necessary for successful freeze drying product and process development. The presentation gives a brief overview of what critical tempe...Read more

The Synergies of Lyostat and Lyotherm

by biopharma-admin in BTL News, BTL Right Sidebar Content

February 2015 Freeze-drying (lyophilization) is a comparatively expensive and time-consuming process and a great deal of emphasis is placed upon improving efficiency and minimizing costs by optimization of the conditions used for freeze-drying. Optimizing Primary Drying [caption id="attachment_3...Read more

Latest Images from the Lyostat4LED

by biopharma-admin in BTL News, BTL Right Sidebar Content

January 2014 The latest generation Freeze-Drying Microscope, Lyostat4LED, is due for launch within the next few weeks. Freeze Drying Microscopy Freeze drying microscopy is an established technique for accurately and easily establishing the point of collapse, the most important critical temperat...Read more