Advanced HPLC Provides Rapid Screening Method Development of Peptides and Oligonucleotides in Drug & Vaccine Discovery

A new era has emerged in HPLC witnessing multiple separation channels merged into single dynamic systems. This approach is now rapidly demonstrating how advantages are not limited to increasing product throughput alone. This article reviews the latest developments of the Sepiatec Sepmatix parallel HPLC system range.

Biomolecules, particularly peptides and oligonucleotide derivatives, are increasingly being utilised throughout medicine. Notably, at present this includes global efforts towards the production of Covid-19 vaccines. Accordingly, requirements for the identification, isolation and purification of potential therapeutic products have increased. Although analytical and preparative HPLC are considered fundamental techniques for these purposes, their limited efficiency can result in significant commercial challenges.

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